Analisis Kejadian Hipertensi Berdasarkan Golongan Darah
Murni Murni(1*), Fitra Mayenti(2)
(1) STIKes Al-Insyirah Pekanbaru
(2) STIKes Al-Insyirah Pekanbaru
(*) Corresponding Author
Abstract
Background: One of the factor that increases the risk of hypertension is ABO blood type. Non-O blood groups have higher vWF levels than blood type O, which can increase the risk of arterial and venous thrombosis. Purpose: The aim of this research is to determine the relationship of blood groups to the incidence of hypertension. Methods: Research is quantitative analitic with cross sectional approach. The study population was elderly who visited Puskesmas Harapan Raya Pekanbaru. The sample was 104 respondents. Sampling technique with purposive sampling. Data analysis using Chi-Square test statistic. Results: Result of research got that blood type Non-O respondent suffer most hypertension amount to 46 people (67,0%). The results showed that there was a significant relationship between blood type with incidence of hypertension with p value < 0,05 (p = 0,005). Conclusion: Blood type O has the lowest vWf level compared to the Non-O blood group, resulting in low coagubility and no blood deposits in the blood vessel wall. Blood type O has a lower risk of hypertension than blood types Non-O (A, B, and AB).
Latar Belakang: Salah satu faktor yang meningkatkan risiko kejadian hipertensi adalah tipe golongan darah ABO. Golongan darah Non-O memiliki kadar vWF lebih tinggi dibandingkan golongan darah O sehingga dapat meningkatkan risiko terjadinya trombosis arteri dan vena. Tujuan Penelitian: Penelitian ini bertujuan untuk mengetahui hubungan golongan darah terhadap kejadian hipertensi. Metode Penelitian: Penelitian bersifat analitik kuantitatif dengan pendekatan cross sectional. Populasi penelitian adalah lansia yang berkunjung ke Puskesmas Harapan Raya Pekanbaru. Sampel penelitian berjumlah 104 responden. Teknik pengambilan sampel yang digunakan adalah purposive sampling. Analisis data menggunakan uji chi-square. Hasil Penelitian: Hasil penelitian didapatkan bahwa responden bergolongan darah Non-O terbanyak menderita hipertensi berjumlah 46 orang (67,0%). Hasil penelitian menunjukkan ada hubungan yang signifikan antara golongan darah dengan kejadian hipertensi dengan nilai p < 0,05 (p = 0,005). Kesimpulan: Golongan darah O memiliki kadar vWf paling rendah dibandingkan golongan darah Non-O, sehingga mengakibatkan koagubilitas rendah dan tidak terdapat endapan darah pada dinding pembuluh darah. Golongan darah O memiliki risiko rendah terhadap kejadian hipertensi dibandingkan golongan darah Non-O (A, B, dan AB).
Keywords
Full Text:
PDFReferences
Adi, L. T. (2007). Terapi herbal berdasarkan golongan darah. Jakarta: Agro Media Pustaka.
BA, D. M., Sow, M. S., Diack, A., Dia, K., Mboup, M. C., Fall, P. D., & Fall, M. D. (2017). Cardiovascular disease and ABO blood-groups in Africans. Are blood-group A individuals at higher risk of ischemic disease?: A pilot study. Egyptian Heart Journal, 69(4), 229–234. https://doi.org/10.1016/j.ehj.2017.03.002
Capuzzo, E., Bonfanti, C., Frattini, F., Montorsi, P., Turdo, R., Previdi, M. G., … Franchini, M. (2016). The relationship between ABO blood group and cardiovascular disease: results from the Cardiorisk program. Annals of Translational Medicine, 4(10), 189–189. https://doi.org/10.21037/atm.2016.03.58
Carpeggiani, C., Coceani, M., Landi, P., Michelassi, C., & Abbate, A. L. (2010). ABO blood group alleles : A risk factor for coronary artery disease . An angiographic study. Atherosclerosis, 211(2), 461–466. https://doi.org/10.1016/j.atherosclerosis.2010.03.012
Dharma, R., Rezeki, S., & Priatni, I. (2006). Disfungsi endotel pada demam berdarah dengue, 10(1), 17–23.
El-sayed, M. K., & Amin, H. (2015). Abo Blood Groups in Correlation With Hyperlipidemia , Diabetes Mellitus Type Ii , and Essential Hypertension, 8(5).
Faranita, T., Trisnawati, Y., & Lubis, M. (2016). Gangguan Koagulasi pada Sepsis. Sari Pediatri, 13(3), 226. https://doi.org/10.14238/sp13.3.2011.226-32
He, M., Wolpin, B., Rexrode, K., Manson, J., Rimm, E., Hu, F., & Qi, L. (2013). NIH Public Access. Arterioscler Thromb Vasc Biol, 32(9), 2314–2320. https://doi.org/10.1161/ATVBAHA.112.248757.ABO
Kemenkes RI. (2014). Info Datin Pusat Data Dan Informasi Kementrian Kesehatan RI. Kemenkes Ri, 109(1), 1–8. https://doi.org/10.1017/CBO9781107415324.004
Larson, N. B., Bell, E. J., Decker, P. A., Pike, M., Wassel, C. L., Tsai, M. Y., … Bielinski, S. J. (2016). ABO blood group associations with markers of endothelial dysfunction in the Multi-Ethnic Study of Atherosclerosis. Atherosclerosis, 251, 422–429. https://doi.org/10.1016/j.atherosclerosis.2016.05.049
Miñano, A., Ordóñez, A., España, F., González-porras, J. R., Lecumberri, R., Fontcuberta, J., … Corral, J. (2008). AB0 blood group and risk of venous or arterial thrombosis in carriers of factor V Leiden or prothrombin G20210A polymorphisms, 93(5), 729–734. https://doi.org/10.3324/haematol.12271
Mishra & Pradhan. (2016). Association Of Maternal ABO Blood Group And Hypertensive Disorders Of Pregnancy. International Journal of Innovative Research in Technology & Science(IJIRTS), 3, Number, 12–16.
Price, S. A., & Wilson, L. M. (2006). Patofisiologi: Konsep klinis prose-proses penyakit. Jakarta: EGC.
Sharif, S., Anwar, N. Farasat , T., & Naz, S. (2014). ABO blood group frequency in Ischemic heart disease patients in Pakistani population. Pak J Med Sci, 30, 2013–2015.
Siddiqui, Z. H., Chaudhry, M. A., Nigar, M., & Butt, H. (2011). a study of association between ABO and Rh blood groups , sex , age and angina pectoris, 23(2), 113–116.
Teng, M., Hsu, L., Wu, S., Chou, H., & Chang, C. (2013). Mediation analysis reveals a sex-dependent association between ABO gene variants and TG / HDL-C ratio that is suppressed by sE-selectin level. Atherosclerosis, 228(2), 406–412. https://doi.org/10.1016/j.atherosclerosis.2013.03.032
Wassmann, S., Bäumer, A. T., Strehlow, K., Eickels, M. Van, Grohé, C., Ahlbory, K., … Nickenig, G. (2001). Endothelial Dysfunction and Oxidative Stress During Estrogen Deficiency in Spontaneously Hypertensive Rats, 435–441.
Copyright (c) 2019 Murni, Fitra Mayenti
This work is licensed under a Creative Commons Attribution 4.0 International License.
Published by Lembaga Layanan Pendidikan Tinggi (LLDIKTI) Wilayah X
Khatib Sulaiman Street Padang
West Sumatera
Phone: +62751705637
Fax: +62751705637
Email: jurnal.lldikti10@ristekdikti.go.id